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Nephritic Syndrome

What is Nephritic Syndrome ?
Rapidly progressive nephritic syndrome is an inflammation of the kidneys that damages the kidney’s filtering mechanisms, called the glomeruli. It is also called rapidly progressive glomerulonephritis.

Causes of Nephritic Syndrome
In many cases, the cause of rapidly progressive nephritic syndrome is unknown. In other cases, the cause appears to be a malfunction of the immune system, which could result from a virus or autoimmune disorder such as systemic lupus erythematosus. The immune system produces infection-fighting proteins, called antibodies, that attack the glomeruli. In some patients, these antibodies affect the kidneys and the lungs, causing a condition called Goodpasture's syndrome.

Symptoms of Nephritic Syndrome
Rapidly progressive nephritic syndrome begins suddenly and gets worse very quickly. Symptoms may be flu-like, such as general fatigue, nausea, vomiting, loss of appetite, fever, and abdominal and joint pain. These types of symptoms can appear for up to one month before symptoms of kidney failure appear.

Diagnosis of Nephritic Syndrome
. Your doctor will check a urine sample for signs of protein and blood, because the damaged glomeruli allow these substances to enter the urine. A blood test will reveal a low red blood cell count (anemia) and a high white blood cell count. Your doctor may also take a small sample of kidney tissue, called a biopsy, to study under a microscope.

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