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Osteomalacia

What is Osteomalacia
Osteomalacia means "soft bones". Osteoid is the bone protein matrix, composed primarily of type 1 collagen. When there is insufficient mineral or osteoblast dysfunction, the osteoid does not mineralize properly, and it accumulates. Many cases of osteomalacia are related to abnormalities in vitamin D.

Causes of Osteomalacia
There are numerous causes of osteomalacia. In children, the condition is called rickets and is usually caused by a deficiency of vitamin D. Conditions that may lead to osteomalacia include inadequate dietary intake of vitamin D, inadequate exposure to sunlight (ultraviolet radiation), which produces vitamin D in the body and malabsorption of vitamin D by the intestines.

Other conditions that can cause osteomalacia include hereditary or acquired disorders of vitamin D metabolism; kidney failure and acidosis.

Symptoms of Osteomalacia
  • Diffuse bone pain, especially in the hips
  • Muscle weakness
  • Bone fractures with minimal trauma
Symptoms associated with low calcium including:
  • Numbness around the mouth
  • Numbness of extremities
  • Spasms of hands or feet
  • Abnormal heart rhythms


Diagnosis of Ostemalacia
  • Blood tests may show low levels of vitamin D
  • Tests may also show low Calcium and Phosphorus levels in the blood
  • Alkaline phosphatase levels can be high


 

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$10.70
 

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