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Vitamin A deficiency

What is Vitamin A deficiency ?
Vitamin A deficiency is a world wide problem that leads to eye diseases, severe infection and death in many people. Most of the affected live in low-income countries.

Laboratory Findings and Diagnosis
Evidence of vitamin A depletion is unobtainable in the preclinical stage, except for a history of inadequate intake. Plasma retinol levels fall after liver stores are exhausted. The normal range is 20 to 80 µg/dL (0.7 to 2.8 µmol/L); 10 to 19 µg/dL (0.35 to 0.66 µmol/L) is low, and < 10 µg/dL (< 0.35 µmol/L) is deficient. Mean plasma retinol binding protein (RBP) is 47 µg/mL for adult males and 42 µg/mL for adult females. Up to the age of 10 yr, the range is 20 to 30 µg/mL. Plasma levels of vitamin A and RBP fall in deficiency states and in acute infections. Other causes of night blindness (eg, retinitis pigmentosa) must be excluded. Secondary infection may complicate the corneal changes. Trial with therapeutic doses of vitamin A assists in the diagnosis.

Signs and symptoms of vitamin A deficiency
Vitamin A deficiency affects the eyes, cells lining the gut and respiratory system. This might result in decreased immune response and growth. The body´s functions and organs that are effected:
  • Sight (xerophtalmia)
  • Immune response
  • Growth
  • Reproduction
  • Skin


 

Products

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