|
|
|
Home -> Shop By Store -> Glucosamine and Chondroitin
Glucosamine and Chondroitin
Glucosamine and Chondroitin:
Glucosamine sulfate and chondroitin sulfate are naturally occurring substances found in the connective tissues of the body, including the cartilage that covers the ends of bones in the joints.
Glucosamine and chondroitin (chondroitin sulphate) supplements have grown in popularity with athletes, because the two compounds are thought to soothe painful joints and decrease the risk of osteoarthritis. Glucosamine and chondroitin are commonly believed to prevent the breakdown of joint cartilage and/or stimulate the production of new cartilage, preserving joint integrity in the face of heavy training.
Glucosamine
Glucosamine is made from glucose (sometimes called 'blood sugar' because of its ubiquitous presence in the blood) and a crystalline amino acid called glutamine. In the human body, it is often incorporated into proteoglycans, which are basically proteins that contain long chains of sugar (glucose) molecules. Proteoglycans are found throughout the body, but they seem to be concentrated mainly in the spaces between cells, including the joints, and they have a strong ability to attract water.
And chondroitin?
Chondroitin sulphate is a 'glycosaminoglycan' (basically, a compound which contains an amino acid attached to a chain of carbohydrate) and is a key component of cartilage. Like glucosamine, chondroitin has a strong affinity for water, and it seems to be able to 'pull' water into joints and thus keep them lubricated. As part of the aging process, the quantity of chondroitin sulphate in joint cartilage tends to decline, and joints become stiffer and less resilient.
What Glucosamine and Chondroitin Does?
Glucosamine and chondroitin sulfate supplements are used to slow the progression of osteoarthritis - the deterioration of cartilage between joint bones - and to reduce the associated pain. Glucosamine is thought to promote the formation and repair of cartilage. Chondroitin is believed to promote water retention and elasticity in cartilage and inhibit enzymes that break down cartilage. In veterinary medicine, glucosamine and chondroitin, often in combination, are commonly used in the treatment of degenerative joint disease- typically in older dogs and cats as well as in horses.
Glucosamine and Chondroitin are Useful
Glucosamine is a popular natural supplement used widely to treat osteoarthritis. However, use of glucosamine has been linked to development of insulin resistance. Glucosamine and chondroitin sulfate given alone or together do not produce insulin resistance or other related perturbations in two rat strains highly sensitive to sugar-induced insulin resistance.
|